Journal article icon

Journal article

The structure of hydrogenase-2 from Escherichia coli: implications for H2-driven proton pumping

Abstract:

Under anaerobic conditions, Escherichia coli is able to metabolize molecular hydrogen via the action of several [NiFe]-hydrogenase enzymes. Hydrogenase-2, which is typically present in cells at low levels during anaerobic respiration, is a periplasmic-facing membrane-bound complex that functions as a proton pump to convert energy from hydrogen (H2) oxidation into a proton gradient; consequently, its structure is of great interest. Empirically, the complex consists of a tightly bound core cata...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1042/BCJ20180053

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Inorganic Chemistry
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Inorganic Chemistry
Finney, AJ More by this author
Lamont, CM More by this author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Inorganic Chemistry
Oxford college:
St Johns College
Expand authors...
Royal Society More from this funder
Dakota Foundation More from this funder
Publisher:
Portland Press Publisher's website
Journal:
Biochemical Journal Journal website
Publication date:
2018-04-16
Acceptance date:
2018-03-19
DOI:
ISSN:
0264-6021
Pubs id:
pubs:847241
URN:
uri:942d3753-ae07-43f0-a8fa-0035fc4cb388
UUID:
uuid:942d3753-ae07-43f0-a8fa-0035fc4cb388
Local pid:
pubs:847241

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP