- Abstract:
-
BACKGROUND: Multiple sclerosis (MS) is a disease that is widely believed to be autoimmune in nature. Genetic-epidemiological studies implicate susceptibility genes in the pathogenesis of MS, although non-MHC susceptibility linkages have been difficult to confirm. Insight into pathways that are intrinsic to other complex diseases has come from the genetic analysis of large, autosomal-dominant kindreds. Here, we present a genetic study of a large and unique kindred in which MS appears to follow...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1136/jnnp.2007.122705
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- Journal:
- Journal of neurology, neurosurgery, and psychiatry
- Volume:
- 79
- Issue:
- 2
- Pages:
- 158-162
- Publication date:
- 2008-02-05
- DOI:
- EISSN:
-
1468-330X
- ISSN:
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0022-3050
- URN:
-
uuid:94122b84-b218-42df-9d2f-33aee077a505
- Source identifiers:
-
33876
- Local pid:
- pubs:33876
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
A genome scan in a single pedigree with a high prevalence of multiple sclerosis.
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