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Are plasma biomarkers of immune activation predictive of HIV progression: a longitudinal comparison and analyses in HIV-1 and HIV-2 infections?

Abstract:

BACKGROUND: Chronic immune activation is a hallmark of HIV infection and has been associated with disease progression. Assessment of soluble biomarkers indicating immune activation provide clues into pathogenesis and hold promise for the development of point-of-care monitoring of HIV in resource-poor-settings. Their evaluation in cohort resources is therefore needed to further their development and use in HIV research. METHODOLOGY/PRINCIPAL FINDINGS: Longitudinal evaluation of βeta-2 microglo...

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Publication status:
Published

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Publisher copy:
10.1371/journal.pone.0044411

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Institution:
University of Oxford
Department:
Oxford, MSD, NPEU
Role:
Author
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Publisher:
Public Library of Science
Journal:
PloS one
Volume:
7
Issue:
9
Pages:
e44411
Publication date:
2012-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:94068371-3810-4fee-b3ef-41413b983b0d
Source identifiers:
350474
Local pid:
pubs:350474

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