Journal article
High strength binding of P815 mastocytoma cells is not necessary for their lysis by macrophages which have been primed and triggered in vitro.
- Abstract:
-
We have examined the hypothesis that binding of P815 mastocytoma cells is a necessary step in lysis of these cells by macrophages which are both "primed" and "triggered" in vitro, Macrophages "primed" by conditioned media containing IFN-gamma, or by rIFN-gamma have an increased ability to bind P815. However, adding either heat-killed Listeria or endotoxin to trigger the primed macrophages has opposite effects on lysis and binding of P815. Lysis is increased. Binding is dramatically decreased....
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Bibliographic Details
- Journal:
- Journal of Immunology
- Volume:
- 141
- Issue:
- 4
- Pages:
- 1083-1090
- Publication date:
- 1988-08-01
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
483521
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:483521
- UUID:
-
uuid:93f8e0e9-42b8-42cb-9d34-6252e3886dd7
- Local pid:
- pubs:483521
- Deposit date:
- 2014-09-11
Terms of use
- Copyright date:
- 1988
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