High strength binding of P815 mastocytoma cells is not necessary for their lysis by macrophages which have been primed and triggered in vitro.

Lu, CY; Lombardi, MJ; Shea, CM; Dustin, L

Abstract:

We have examined the hypothesis that binding of P815 mastocytoma cells is a necessary step in lysis of these cells by macrophages which are both "primed" and "triggered" in vitro, Macrophages "primed" by conditioned media containing IFN-gamma, or by rIFN-gamma have an increased ability to bind P815. However, adding either heat-killed Listeria or endotoxin to trigger the primed macrophages has opposite effects on lysis and binding of P815. Lysis is increased. Binding is dramatically decreased....

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APA Style

Lu, C. Y., Lombardi, M. J., Shea, C. M., & Dustin, L. (1988). High strength binding of P815 mastocytoma cells is not necessary for their lysis by macrophages which have been primed and triggered in vitro. Journal of Immunology (Baltimore, Md. : 1950), 141(4), 1083–1090.

MLA Style

Lu, C. Y., et al. “High Strength Binding of P815 Mastocytoma Cells Is Not Necessary for Their Lysis by Macrophages Which Have Been Primed and Triggered in Vitro.” Journal of Immunology (Baltimore, Md. : 1950), vol. 141, no. 4, 1988, pp. 1083–90.

Chicago Style

Lu, CY, MJ Lombardi, CM Shea, and L Dustin. 1988. “High Strength Binding of P815 Mastocytoma Cells Is Not Necessary for Their Lysis by Macrophages Which Have Been Primed and Triggered in Vitro.” Journal of Immunology (Baltimore, Md. : 1950) 141 (4): 1083–90.
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