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Journal article

Adult and embryonic blood and endothelium derive from distinct precursor populations which are differentially programmed by BMP in Xenopus.

Abstract:

Blood and blood vessels develop in close association in vertebrate embryos and loss-of-function mutations suggest common genetic regulation. By the criteria of co-expression of blood and endothelial genes, and lineage tracing of progeny, we locate two distinct populations of progenitors for blood and endothelial cells in developing Xenopus embryos. The first population is located immediately posterior to the cement gland during neurula stages and gives rise to embryonic blood and vitelline ve...

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Publication status:
Published

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Publisher copy:
10.1242/dev.00169

Authors


Walmsley, M More by this author
Ciau-Uitz, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, BHF Centre of Research Excellence
Journal:
Development (Cambridge, England)
Volume:
129
Issue:
24
Pages:
5683-5695
Publication date:
2002-12-05
DOI:
EISSN:
1477-9129
ISSN:
0950-1991
URN:
uuid:93e65f4a-b556-4848-8431-c852f79385d6
Source identifiers:
106349
Local pid:
pubs:106349

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