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Analysis of successful immune responses in persons infected with hepatitis C virus.

Abstract:

Although hepatitis C virus (HCV) infection is very common, identification of patients during acute infection is rare. Consequently, little is known about the immune response during this critical stage of the disease. We analyzed the T lymphocyte response during and after acute resolving HCV infection in three persons, using interferon (IFN)-gamma enzyme-linked immunospot (ELISPOT) and human histocompatibility leukocyte antigen (HLA) peptide tetramer assays. Acute infection was associated with...

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Publication status:
Published

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Publisher copy:
10.1084/jem.191.9.1499

Authors


Lechner, F More by this author
Dunbar, PR More by this author
Chapman, R More by this author
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Journal:
The Journal of experimental medicine
Volume:
191
Issue:
9
Pages:
1499-1512
Publication date:
2000-05-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:93e4fba9-555d-4bbf-8c00-716c976e50fd
Source identifiers:
3327
Local pid:
pubs:3327

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