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Journal article

Cortisol modulation of 5-HT-mediated growth hormone release in recovered depressed patients.

Abstract:

BACKGROUND: Recent formulations of the pathophysiology of major depression suggest that stress-induced cortisol secretion may lower brain serotonin (5-HT) function, thereby precipitating depressive symptomatology. This implies that people who develop depression after stressful life events may be particularly vulnerable to the effect of cortisol on brain 5-HT activity. We therefore assessed the effect of a single dose of hydrocortisone on 5-HT-mediated growth hormone (GH) release in healthy v...

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Publication status:
Published

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Journal:
Journal of affective disorders
Volume:
72
Issue:
3
Pages:
249-255
Publication date:
2002-12-05
DOI:
EISSN:
1573-2517
ISSN:
0165-0327
URN:
uuid:93d747f0-f2cf-4df2-aac7-79cc51e7f360
Source identifiers:
185783
Local pid:
pubs:185783

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