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Thesis

Regulation of class II pilin gene expression in Neisseria meningitidis

Abstract:

Neisseria meningitidis expresses multi-component organelles called Type four pili (Tfp), which are key virulence factors involved in interactions with host cells. Pilin (PilE) is the main component of Tfp and N. meningitidis can express either class I pilins that undergo antigenic variation or class II pilins, which are highly conserved. The region upstream of the pilE gene contains two putative promoters which are recognised by distinct sigma factors: sigma...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:939cc3a9-d389-4c94-9a14-800854320a20
Deposit date:
2019-02-26

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