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Effects of seven-day diazepam administration on resting-state functional connectivity in healthy volunteers: a randomized, double-blind study.

Abstract:

RATIONALE: Benzodiazepines, such as diazepam, are anxiolytic-sedative drugs, used for the treatment of several different disorders. The pharmacological mechanism of action of benzodiazepines is well understood; however, it remains unclear which neural networks and systems are involved in translating these neurochemical actions into their therapeutic effects. OBJECTIVES: The objective of this study was to investigate the effects of 7-day diazepam administration compared to placebo on resting-s...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s00213-014-3844-3

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
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Medical Research Council More from this funder
Publisher:
Springer Berlin Heidelberg Publisher's website
Journal:
Psychopharmacology Journal website
Volume:
232
Issue:
12
Pages:
2139-2147
Publication date:
2014-12-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:939186c0-8b82-47bf-9f76-2efe9aab1557
Source identifiers:
502754
Local pid:
pubs:502754

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