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Neuroprotection for ischaemic stroke: translation from the bench to the bedside.

Abstract:

Neuroprotection seeks to restrict injury to the brain parenchyma following an ischaemic insult by preventing salvageable neurons from dying. The concept of neuroprotection has shown promise in experimental studies, but has failed to translate into clinical success. Many reasons exist for this including the heterogeneity of human stroke and the lack of methodological agreement between preclinical and clinical studies. Even with the proposed Stroke Therapy Academic Industry Roundtable criteria ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford
Minnerup, J More by this author
Balami, JS More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Stroke and Geratology
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Journal:
International journal of stroke : official journal of the International Stroke Society
Volume:
7
Issue:
5
Pages:
407-418
Publication date:
2012-07-05
DOI:
EISSN:
1747-4949
ISSN:
1747-4930
URN:
uuid:938073ec-bcaf-4919-b0c2-421fac4dbb2f
Source identifiers:
316392
Local pid:
pubs:316392

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