- Abstract:
-
Chronic corticosteroid treatment is known to induce bone loss and osteoporosis. Osteoclasts are specialised bone-resorbing cells that are formed from mononuclear phagocyte precursors that circulate in the monocyte fraction. In this study we have examined the effect of the synthetic glucocorticoid, dexamethasone, on human osteoclast formation and bone-resorbing activity. Human monocytes were cultured for up to 21 days on glass coverslips and dentine slices, with soluble receptor activator for ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1677/joe.0.1750155
-
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- Journal:
- The Journal of endocrinology
- Volume:
- 175
- Issue:
- 1
- Pages:
- 155-163
- Publication date:
- 2002-10-05
- DOI:
- EISSN:
-
1479-6805
- ISSN:
-
0022-0795
- URN:
-
uuid:937dd85e-cf6e-4e7d-9b6f-2d60af07f6bb
- Source identifiers:
-
103835
- Local pid:
- pubs:103835
- Copyright date:
- 2002
Journal article
Effect of corticosteroids on human osteoclast formation and activity.
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