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Guided principal component analysis (GPCA): a simple method for improving detection of a known analyte

Abstract:

There is increasing interest in the application of Raman spectroscopy in a medical setting, ranging from supporting real-time clinical decisions e.g. surgical margins to assisting pathologists with disease classification. However, there remain a number of barriers for adoption in the medical setting due to the increased complexity of probing highly heterogeneous, dynamic biological materials. This inherent challenge can also limit the deployment of higher level analytical approaches such as A...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/d3an00820g

Authors


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Role:
Author
ORCID:
0000-0002-7223-9585
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Role:
Author
ORCID:
0009-0001-6966-1902
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0003-0912-5339
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Role:
Author
ORCID:
0000-0001-5603-3731
Publisher:
Royal Society of Chemistry
Journal:
Analyst More from this journal
Volume:
149
Issue:
1
Pages:
205-211
Place of publication:
England
Publication date:
2023-11-28
Acceptance date:
2023-11-06
DOI:
EISSN:
1364-5528
ISSN:
0003-2654
Pmid:
38014742
Language:
English
Keywords:
Pubs id:
1574597
Local pid:
pubs:1574597
Deposit date:
2024-02-21

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