Prevalence, incidence and predictors of severe anaemia with zidovudine-containing regimens in African adults with HIV infection within the DART trial.

Journal article

OBJECTIVE: To describe the prevalence, incidence and predictors of severe anaemia in previously untreated symptomatic HIV-infected adults with CD4+ T-cells <200 cells/mm(3) initiating zidovudine-containing regimens in Africa. DESIGN: DART is a randomized trial comparing two strategies for HIV/AIDS management in Uganda and Zimbabwe. METHODS: We analysed the occurrence of anaemia at weeks 4 and 12, and then every 12 weeks. We also evaluated sex, age, WHO stage, body mass index (BMI), baselin...

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Authors: Ssali, F; Stöhr, W; Munderi, P; Reid, A; Walker, A

• Publication status: Published
• Journal: Antiviral therapy
• Volume: 11
• Issue: 6
• Pages: 741-749
• Publication date: 2006-01-01
• EISSN: 2040-2058
• ISSN: 1359-6535
• Language: English
• Keywords: Humans; Incidence; Severity of Illness Index; Zidovudine; Adult; Hemoglobins; Prevalence; Female; HIV Infections; Uganda; Anti-HIV Agents; Reverse Transcriptase Inhibitors; DART Trial Team; Predictive Value of Tests; Anemia; Drug Therapy, Combination; Zimbabwe; Male