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Journal article

Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach.

Abstract:

A critical step in the dissemination of ovarian cancer is the formation of multicellular spheroids from cells shed from the primary tumour. The objectives of this study were to apply bioengineered three-dimensional (3D) microenvironments for culturing ovarian cancer spheroids in vitro and simultaneously to build on a mathematical model describing the growth of multicellular spheroids in these biomimetic matrices. Cancer cells derived from human epithelial ovarian carcinoma were embedded withi...

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Publication status:
Published

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Publisher copy:
10.1039/c3ib20252f

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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
Journal:
Integrative biology : quantitative biosciences from nano to macro
Volume:
5
Issue:
3
Pages:
597-605
Publication date:
2013-03-05
DOI:
EISSN:
1757-9708
ISSN:
1757-9694
URN:
uuid:932e1c03-bed8-49c9-ae46-27cbf0fdcf3b
Source identifiers:
384329
Local pid:
pubs:384329

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