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Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.

Abstract:

Myelin is a multilayered membrane that ensheathes axonal fibers in the vertebrate nervous system, allowing fast propagation of nerve action potentials. It contains densely packed lipids, lacks an actin-based cytocortex, and requires myelin basic protein (MBP) as its major structural component. This protein is the basic constituent of the proteinaceous meshwork that is localized between adjacent cytoplasmic membranes of the myelin sheath. Yet, it is not clear how MBP influences the organizatio...

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Publication status:
Published

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Publisher copy:
10.1016/j.bpj.2016.04.047

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Department:
Cellular Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany.
Journal:
Biophysical journal
Issue:
11
Publication date:
2016-06-05
DOI:
ISSN:
1542-0086 and 0006-3495
Pubs id:
pubs:628380
URN:
uri:9304f9ec-e18f-40b2-a0db-1b6128c9c03c
UUID:
uuid:9304f9ec-e18f-40b2-a0db-1b6128c9c03c
Local pid:
pubs:628380
Language:
English
Keywords:

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