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Dendritic secretion of peptides from hypothalamic magnocellular neurosecretory neurones: a local dynamic control system and its functions.

Abstract:

The role of the dendrites of magnocellular neurones in the release of neurosecretory peptides and the synthesis of many proteins locally is reviewed. Oxytocin and vasopressin contained in dense-cored neurosecretory vesicles are released from magnocellular dendrites not only by excitatory transmitters such as glutamate acting through well-established receptors, but also by a rapid action of oestradiol acting by a mechanism which appears to involve NMDA receptors. Magnocellular dendrites also c...

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Publication status:
Published

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Journal:
Experimental physiology
Volume:
85 Spec No
Issue:
s1
Pages:
131S-138S
Publication date:
2000-03-05
DOI:
EISSN:
1469-445X
ISSN:
0958-0670
URN:
uuid:92ecf411-5025-4e2d-b098-314af1ebd18e
Source identifiers:
114061
Local pid:
pubs:114061

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