Patients who require dialysis are at high risk for cardiovascular mortality, which may be improved by mineralocorticoid receptor antagonists (MRAs).Systematic review and meta-analysis of randomized controlled trials.Adults undergoing long-term hemodialysis or peritoneal dialysis with or without heart failure.Randomized controlled trials evaluating an MRA in dialysis and reported at least one outcome of interest.Spironolactone (8 trials) or eplerenone (1 trial) compared to placebo (7 trials) o...Expand abstract
- Publication status:
- Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada.
- American journal of kidney diseases : the official journal of the National Kidney Foundation
- Publication date:
0272-6386 and 1523-6838
- Pubs id:
- Local pid:
- Copyright date:
The Safety and Efficacy of Mineralocorticoid Receptor Antagonists in Patients Who Require Dialysis: A Systematic Review and Meta-analysis.
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