- Abstract:
-
The prospect of exploiting mathematical and computational models to gain insight into the influence of scheduling on cancer chemotherapeutic effectiveness is increasingly being considered. However, the question of whether such models are robust to the inclusion of additional tumour biology is relatively unexplored. In this paper, we consider a common strategy for improving protocol scheduling that has foundations in mathematical modelling, namely the concept of dose densification, whereby res...
Expand abstract - Publisher copy:
- 10.1093/imammb/dqr004
-
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- Journal:
- Mathematical medicine and biology : a journal of the IMA
- Volume:
- 28
- Issue:
- 4
- Pages:
- 357-384
- Publication date:
- 2011-12-05
- DOI:
- EISSN:
-
1477-8602
- ISSN:
-
1477-8599
- URN:
-
uuid:92c93d14-8a23-40a7-b02f-0b380e8a8c44
- Source identifiers:
-
130835
- Local pid:
- pubs:130835
- Copyright date:
- 2011
Journal article
The influence of toxicity constraints in models of chemotherapeutic protocol escalation.
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