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Thesis

Evaluation of the non-specific effects of Bacille Calmette-Guérin (BCG) vaccination in healthy UK adults

Abstract:

Tuberculosis is the leading single infectious disease killer in the world, and the global burden of LTBI and TB disease, with the addition of antimicrobial drug resistance means there is a desperate need for a safe and effective TB vaccine. BCG is the only licensed vaccine and extremely variable in efficacy. However, BCG potentially exerts a non-specific beneficial effect - protecting infants from other causes of death such as respiratory infections and fever. Data from randomised and o...

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Department:
Helen McShane
Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Project
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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