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Antifibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological malignancies (Review).

Abstract:

Background Patients with haematological disorders are frequently at risk of severe or life-threatening bleeding as a result of thrombocytopenia. This is despite the routine use of prophylactic platelet transfusions (PlTx) to prevent bleeding once the platelet count falls below a certain threshold. PlTx are not without risk and adverse events may be life-threatening. A possible adjunct to prophylactic PlTxs is the use of antifibrinolytics, specifically the lysine analogues tranexamic acid (TX...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/14651858.CD009733.pub2

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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German Ministry of Education and Research More from this funder
Publisher:
Wiley Publisher's website
Journal:
Cochrane Database of Systematic Reviews Journal website
Volume:
2013
Issue:
7
Pages:
CD009733
Chapter number:
UNSP CD009733
Publication date:
2013-07-29
DOI:
EISSN:
1469-493X
ISSN:
1469-493X
URN:
uuid:92a68372-9345-49b8-a377-26b7ff796548
Source identifiers:
389997
Local pid:
pubs:389997

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