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Journal article

Inflammatory arthritis and dermatitis in thymectomized, CD25+ cell-depleted adult mice.

Abstract:

OBJECTIVE: To investigate the effect of CD25+ or CTLA-4(+) cell depletion on the natural history of collagen-induced and spontaneous arthritis in male DBA1/J mice. METHODS: Male DBA/1J mice were treated with anti-CD25 depleting antibody (PC61) or isotype control (GL113), or with anti-CTLA-4 depleting antibody (4F10) at various time-points peri- and post-immunization with bovine collagen type II, emulsified in adjuvant. In order to develop a model system in which long-term depletion of CD25+ r...

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Publication status:
Published

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Publisher copy:
10.1093/rheumatology/keh477

Authors


Journal:
Rheumatology (Oxford, England)
Volume:
44
Issue:
3
Pages:
299-308
Publication date:
2005-03-05
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
URN:
uuid:92a053f7-97e1-41dc-95ea-bd9b496fc60e
Source identifiers:
107772
Local pid:
pubs:107772

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