Journal article
Dictyostelium as a model to assess site-specific ADP-ribosylation events
- Abstract:
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The amoeba Dictyostelium discoideum is a single-cell organism that can undergo a simple developmental program, making it an excellent model to study the molecular mechanisms of cell motility, signal transduction, and cell-type differentiation. A variety of human genes that are absent or show limited conservation in other invertebrate models have been identified in this organism. This includes ADP-ribosyltransferases, also known as poly-ADP-ribose polymerases (PARPs), a family of proteins that...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 721.1KB, Terms of use)
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- Publisher copy:
- 10.1007/978-1-4939-8588-3_9
Authors
Funding
+ National Centre for the Replacement, Refinement and Reduction of Animals in Research
More from this funder
Funding agency for:
Pears, C
Grant:
NC/M000834/1
NC/K00137X/1
Bibliographic Details
- Publisher:
- Humana Press
- Series:
- Methods in Molecular Biology
- Journal:
- ADP-ribosylation and NAD+ Utilizing Enzymes More from this journal
- Volume:
- 1813
- Pages:
- 125-148
- Publication date:
- 2018-08-11
- DOI:
- ISSN:
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1064-3745
- Pmid:
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30097865
- ISBN:
- 9781493985876
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:909911
- UUID:
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uuid:9294c8bc-0539-4db9-b9b5-11a98d38e882
- Local pid:
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pubs:909911
- Source identifiers:
-
909911
- Deposit date:
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2018-10-30
Terms of use
- Copyright holder:
- Springer Science+Business Media, LLC, part of Springer Nature
- Copyright date:
- 2018
- Notes:
- Copyright © Springer Science+Business Media, LLC, part of Springer Nature 2018. This is the accepted manuscript version of the article. The final version is available online from Springer at: https://doi.org/10.1007/978-1-4939-8588-3_9
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