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RNA-Seq dataset generated from stimulation of cultured Tc2 cells

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The purpose of this data is to investigate the transcriptional response of type 2 CD8+ T cells to different modes of activation. Tc2 cells were isolated by FACS sorting CRTH2+ CD8+ T cells from cone PBMCs. They were expanded using anti-CD3 and IL-2 for 3 weeks in RPMI + 10% FCS. They were stimulated either with anti-CD3 + anti-CD28, PGD2, or a combination of alarmin cytokines (IL-25, IL-33, and TSLP). Total RNA was isolated and analysed by RNA-seq. This file includes the read counts, the...

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Authors/Creators


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Creator, Data collector, Depositor

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Principal Investigator (PI)
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Grant:
BRT00030
Programme:
MRC-DTP Studentship (Oxford)
Publisher:
University of Oxford
Publication date:
2021
DOI:
Language:
English
Keywords:
Subjects:
Deposit date:
2021-03-05

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