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Increased cerebral blood volume in HIV-positive patients detected by functional MRI.

Abstract:

OBJECTIVE: To study changes in cerebral hemodynamics related to HIV infection. BACKGROUND: Cerebral injury is a well-known manifestation of HIV infection. Physiologic changes in the HIV brain may precede structural changes and may be detected by functional MRI (fMRI). METHODS: Dynamic contrast fMRI was used to measure the cerebral blood volume (CBV) in 13 patients infected with HIV and in 7 healthy control subjects. RESULTS: Significant increases in dynamic CBV were found in the deep (p < ...

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Publication status:
Published

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Publisher copy:
10.1212/wnl.50.6.1821

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Neurology
Volume:
50
Issue:
6
Pages:
1821-1826
Publication date:
1998-06-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:9249afc9-83f7-4952-9641-181c6bdeed49
Source identifiers:
376233
Local pid:
pubs:376233

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