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Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials

Abstract:

Background Neoadjuvant chemotherapy (NACT) for early breast cancer can make breast-conserving surgery more feasible and might be more likely to eradicate micrometastatic disease than might the same chemotherapy given after surgery. We investigated the long-term benefits and risks of NACT and the influence of tumour characteristics on outcome with a collaborative meta-analysis of individual patient data from relevant randomised trials.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S1470-2045(17)30777-5

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Publisher:
Elsevier
Journal:
Lancet Oncology More from this journal
Volume:
19
Issue:
1
Pages:
27–39
Publication date:
2017-12-11
Acceptance date:
2017-09-25
DOI:
EISSN:
1474-5488
ISSN:
1470-2045
Language:
English
Pubs id:
pubs:734745
UUID:
uuid:92484e3b-8216-442f-8e6d-8dda0547c509
Local pid:
pubs:734745
Source identifiers:
734745
Deposit date:
2017-10-09

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