- Abstract:
-
Discontinuation of angiotensin-converting enzyme (ACE) inhibitor is recommended if patients experience ≥30% acute increase in serum creatinine after starting this therapy. However, the long-term effects of its continuation or discontinuation on major clinical outcomes after increases in serum creatinine are unclear. In the ADVANCE trial (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation), 11 140 diabetes mellitus patients were randomly assi...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(pdf, 193.7kb)
-
- Publisher copy:
- 10.1161/HYPERTENSIONAHA.118.12060
-
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- Funding agency for:
- Woodward, M
- Publisher:
- American Heart Association Publisher's website
- Journal:
- Hypertension Journal website
- Volume:
- 73
- Issue:
- 1
- Pages:
- 84-91
- Publication date:
- 2018-11-27
- Acceptance date:
- 2018-10-25
- DOI:
- EISSN:
-
1524-4563
- ISSN:
-
0194-911X
- Pubs id:
-
pubs:935227
- URN:
-
uri:92368217-252c-41eb-8433-fc85765ca4b3
- UUID:
-
uuid:92368217-252c-41eb-8433-fc85765ca4b3
- Local pid:
- pubs:935227
- Copyright holder:
- American Heart Association, Inc.
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 American Heart Association, Inc. This is the accepted manuscript version of the article. The final version is available online from American Heart Association at: https://doi.org/10.1161/HYPERTENSIONAHA.118.12060
Journal article
Acute increases in serum creatinine after starting angiotensin-converting enzyme inhibitor-based therapy and effects of its continuation on major clinical outcomes in type 2 diabetes mellitus: the ADVANCE trial
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+ National Health and Medical Research Council of Australia
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