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The effect of infectious dose on humoral and cellular immune responses in Chlamydophila caviae primary ocular infection

Abstract:

Following infection, the balance between protective immunity and immunopathology often depends on the initial infectious load. Several studies have investigated the effect of infectious dose; however, the mechanism by which infectious dose affects disease outcomes and the development of a protective immune response is not known. The aim of this study was to investigate how the infectious dose modulates the local and systemic humoral and the cellular immune responses during primary ocular chla...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0180551

Authors


Filipovic, A More by this author
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ORCID:
0000-0003-1019-6572
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ORCID:
0000-0001-7854-3812
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ORCID:
0000-0002-1240-506X
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Austrian Federal Ministry of Economy More from this funder
Ministry of Education, Science, and Technological Development of the Republic of Serbia More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
12
Issue:
7
Pages:
e0180551
Publication date:
2017-07-05
Acceptance date:
2017-06-16
DOI:
ISSN:
1932-6203
Pubs id:
pubs:924910
URN:
uri:922c541d-966c-4cc3-8230-f07e8bae65b9
UUID:
uuid:922c541d-966c-4cc3-8230-f07e8bae65b9
Local pid:
pubs:924910

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