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Comparing model-based and model-free analysis methods for QUASAR arterial spin labeling perfusion quantification.

Abstract:

Amongst the various implementations of arterial spin labeling MRI methods for quantifying cerebral perfusion, the QUASAR method is unique. By using a combination of labeling with and without flow suppression gradients, the QUASAR method offers the separation of macrovascular and tissue signals. This permits local arterial input functions to be defined and "model-free" analysis, using numerical deconvolution, to be used. However, it remains unclear whether arterial spin labeling data are best ...

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Publication status:
Published

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Publisher copy:
10.1002/mrm.24372

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Journal:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine
Volume:
69
Issue:
5
Pages:
1466-1475
Publication date:
2013-05-01
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
Source identifiers:
339853

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