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Lymphocyte sub-populations in human cord blood: analysis with monoclonal antibodies.

Abstract:
Lymphocytes and monocytes in human cord blood have been analysed using a panel of fourteen monoclonal antibodies. Contrary to earlier data based on the sheep erythrocyte rosette assay for T cells, no marked deficit in T cells was found in cord as compared with adult blood. The T cells in cord blood had a relatively immature phenotype whereas B cells showed a mature phenotype. The phenotypic differences between adult and cord blood appear minor in relation to the marked functional differences reported by others.

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Authors


Bradley, J More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Journal:
Journal of reproductive immunology
Volume:
5
Issue:
5
Pages:
311-317
Publication date:
1983-09-05
DOI:
EISSN:
1872-7603
ISSN:
0165-0378
URN:
uuid:9214434c-2dd0-4412-baab-215d4148373c
Source identifiers:
35515
Local pid:
pubs:35515

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