Conference item
Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth.
- Abstract:
-
Maternal vitamin D deficiency has been associated with reduced offspring bone mineral accrual. Retinoid-X receptor-alpha (RXRA) is an essential cofactor in the action of 1,25-dihydroxyvitamin D (1,25[OH]2 -vitamin D), and RXRA methylation in umbilical cord DNA has been associated with later offspring adiposity. We tested the hypothesis that RXRA methylation in umbilical cord DNA collected at birth is associated with offspring skeletal development, assessed by dual-energy X-ray absorptiometry,...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/jbmr.2056
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Bibliographic Details
- Volume:
- 29
- Issue:
- 3
- Pages:
- 600-607
- Host title:
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- Publication date:
- 2014-03-01
- Event location:
- United States
- DOI:
- EISSN:
-
1523-4681
- ISSN:
-
0884-0431
- Source identifiers:
-
135070
Item Description
- Keywords:
- Pubs id:
-
pubs:135070
- UUID:
-
uuid:9203f4e8-5098-4845-ac03-bc211c2e7cb1
- Local pid:
- pubs:135070
- Deposit date:
- 2013-11-17
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- Copyright date:
- 2014
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