- Abstract:
-
Maternal vitamin D deficiency has been associated with reduced offspring bone mineral accrual. Retinoid-X receptor-alpha (RXRA) is an essential cofactor in the action of 1,25-dihydroxyvitamin D (1,25[OH]2 -vitamin D), and RXRA methylation in umbilical cord DNA has been associated with later offspring adiposity. We tested the hypothesis that RXRA methylation in umbilical cord DNA collected at birth is associated with offspring skeletal development, assessed by dual-energy X-ray absorptiometry,...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/jbmr.2056
-
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- Volume:
- 29
- Issue:
- 3
- Pages:
- 600-607
- Publication date:
- 2014-03-05
- DOI:
- EISSN:
-
1523-4681
- ISSN:
-
0884-0431
- URN:
-
uuid:9203f4e8-5098-4845-ac03-bc211c2e7cb1
- Source identifiers:
-
135070
- Local pid:
- pubs:135070
- Copyright date:
- 2014
Conference
Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth.
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