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The African enigma: low prevalence of gastric atrophy, high prevalence of chronic inflammation in West African adults and children.

Abstract:

BACKGROUND: Helicobacter pylori infection is very common in Africa, yet peptic ulcer disease and gastric malignancy are rare. AIM: The aim of this study was to quantify mucosal responses to H. pylori in Gambian adults and children and to estimate the prevalence of antibodies to bacterial virulence factors (cagA and vacA) in a symptomatic population. PATIENTS AND METHODS: Adults (mean 36 SD 12 years) with dyspepsia and children (mean 1.4 years SD 0.4 years) with malnutrition underwent gastrosc...

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Authors


Campbell, DI More by this author
Warren, BF More by this author
Thomas, JE More by this author
Telford, JL More by this author
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Journal:
Helicobacter
Volume:
6
Issue:
4
Pages:
263-267
Publication date:
2001-12-05
DOI:
EISSN:
1523-5378
ISSN:
1083-4389
URN:
uuid:91fdd1c9-964f-4596-b18f-ffc4588acb8e
Source identifiers:
191037
Local pid:
pubs:191037

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