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Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.

Abstract:

BACKGROUND: Autism spectrum disorders (ASDs) are a group of highly heritable neurodevelopmental disorders which are characteristically comprised of impairments in social interaction, communication and restricted interests/behaviours. Several cell adhesion transmembrane leucine-rich repeat (LRR) proteins are highly expressed in the nervous system and are thought to be key regulators of its development. Here we present an association study analysing the roles of four promising candidate genes -...

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Publication status:
Published

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Publisher copy:
10.1186/2040-2392-1-7

Authors


Pagnamenta, AT More by this author
Mulder, EJ More by this author
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Journal:
Molecular autism
Volume:
1
Issue:
1
Pages:
7
Publication date:
2010
DOI:
EISSN:
2040-2392
ISSN:
2040-2392
URN:
uuid:91b024ea-2f3b-4e73-99e9-8915dfd3e4b8
Source identifiers:
66082
Local pid:
pubs:66082

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