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Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen.

Abstract:

UNLABELLED: Despite intense efforts to develop radiotracers to detect cancers or monitor treatment response, few are widely used as a result of challenges with demonstrating clear clinical use. We reasoned that a radiotracer targeting a validated clinical biomarker could more clearly assess the advantages of imaging cancer. The virtues and shortcomings of measuring secreted prostate-specific antigen (PSA), an androgen receptor (AR) target gene, in patients with prostate cancer are well docume...

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Journal:
Cancer discovery More from this journal
Volume:
2
Issue:
4
Pages:
320-327
Publication date:
2012-04-01
DOI:
EISSN:
2159-8290
ISSN:
2159-8274
Language:
English
Keywords:
Pubs id:
pubs:365850
UUID:
uuid:9179872b-2389-4351-825e-b119f567c6f4
Local pid:
pubs:365850
Source identifiers:
365850
Deposit date:
2013-11-16

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