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Journal article

Evidence of axonal damage in human acute demyelinating diseases.

Abstract:

Substantial axon damage, detected by immunostaining for beta amyloid precursor protein (betaAPP) has been demonstrated in acute demyelinating lesions in multiple sclerosis. AIMS: The present study aimed to determine if this was also the case in the other human acute demyelinating diseases, acute hemorrhagic leucoencephalitis (AHLE), acute disseminated encephalomyelitis (ADEM) and central pontine myelinolysis (CPM). METHODS: BetaAPP immunostaining was used as a marker of axonal damage in autop...

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Publication status:
Published

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Publisher copy:
10.1016/j.jns.2004.03.032

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of the neurological sciences
Volume:
222
Issue:
1-2
Pages:
29-34
Publication date:
2004-07-01
DOI:
EISSN:
1878-5883
ISSN:
0022-510X
Source identifiers:
242878

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