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Molecular machines in archaeal DNA replication.

Abstract:

The archaeal DNA replication apparatus is a simplified version of that of eukaryotes and has attracted attention as a tractable model system for the orthologous, but significantly more complex eukaryal machinery. A variety of archaeal model organisms have been investigated with strong emphasis on structural and biochemical analyses of replication-associated proteins. In this review we will describe recent advances in understanding the properties of the replicative helicase, the MCM complex, a...

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Publication status:
Published

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Publisher copy:
10.1016/j.cbpa.2011.07.017

Authors


Beattie, TR More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Current opinion in chemical biology
Volume:
15
Issue:
5
Pages:
614-619
Publication date:
2011-10-05
DOI:
EISSN:
1879-0402
ISSN:
1367-5931
URN:
uuid:9155b405-47bc-400a-b385-a26601ae2eb4
Source identifiers:
172047
Local pid:
pubs:172047

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