3'-5'-Cyclic adenosine monophosphate (cAMP) is a pleiotropic intracellular second messenger generated in response to activation of G(s) protein-coupled receptors. In the heart, cAMP mediates the catecholaminergic control on heart rate and contractility but, at the same time, it is responsible for the functional response to a wide variety of other hormones and neurotransmitters, raising the question of how the myocyte can decode the cAMP signal and generate the appropriate functional output to...Expand abstract
- Publisher copy:
- Copyright date:
cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies.
If you are the owner of this record, you can report an update to it here: Report update to this record