- Abstract:
-
OBJECTIVES: To determine the role of systemic complement activation in the pathogenesis of age-related macular degeneration and to examine whether serum C3a des Arg reflects systemic complement activation, independent of individual complement component levels. METHODS: Plasma complement C3a des Arg levels and a single nucleotide polymorphism at position 402 of the complement factor H gene (CFH) were determined in 3 groups of subjects: 42 subjects with early age-related maculopathy, 42 subjec...
Expand abstract - Publisher copy:
- 10.1001/archopht.125.4.515
-
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- Journal:
- Archives of ophthalmology
- Volume:
- 125
- Issue:
- 4
- Pages:
- 515-519
- Publication date:
- 2007-04-05
- DOI:
- EISSN:
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1538-3601
- ISSN:
-
0003-9950
- URN:
-
uuid:91020e2b-8168-43a2-b30b-878d76834452
- Source identifiers:
-
254191
- Local pid:
- pubs:254191
- Copyright date:
- 2007
Journal article
Estimation of systemic complement C3 activity in age-related macular degeneration.
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