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Journal article

Estimation of systemic complement C3 activity in age-related macular degeneration.

Abstract:

OBJECTIVES: To determine the role of systemic complement activation in the pathogenesis of age-related macular degeneration and to examine whether serum C3a des Arg reflects systemic complement activation, independent of individual complement component levels. METHODS: Plasma complement C3a des Arg levels and a single nucleotide polymorphism at position 402 of the complement factor H gene (CFH) were determined in 3 groups of subjects: 42 subjects with early age-related maculopathy, 42 subjec...

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Publisher copy:
10.1001/archopht.125.4.515

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Journal:
Archives of ophthalmology
Volume:
125
Issue:
4
Pages:
515-519
Publication date:
2007-04-05
DOI:
EISSN:
1538-3601
ISSN:
0003-9950
URN:
uuid:91020e2b-8168-43a2-b30b-878d76834452
Source identifiers:
254191
Local pid:
pubs:254191

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