Journal article
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
- Abstract:
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Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide association studies in 39,883 individuals of European ancestry to identify genes associated with metabolic disease. We identified 8 novel loci associated with adiponectin levels and confirmed 2 previously reported loci (P=4.5x10(-8)-1.2x10(-43)). Using a n...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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(pdf, 772.0KB)
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- Publisher copy:
- 10.1371/journal.pgen.1002607
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Authors
Funding
+ Sir Henry Wellcome Postdoctoral Research Fellow
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Funding agency for:
Perry, JR
National Institutes of Health
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National Institute on Aging
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The Netherlands Organisation for Scientific Research
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Erasmus Medical Center
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS genetics Journal website
- Volume:
- 8
- Issue:
- 3
- Pages:
- Article: e1002607
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
- URN:
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uuid:91016d81-3803-4c00-aa5c-1a3e43c054de
- Source identifiers:
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322832
- Local pid:
- pubs:322832
- Paper number:
- 3
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Dastani et al.
- Copyright date:
- 2012
- Notes:
- Copyright 2012 Dastani et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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