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Human ventricular fibrillation during global ischemia and reperfusion: paradoxical changes in activation rate and wavefront complexity.

Abstract:

BACKGROUND: Ischemic ventricular fibrillation in experimental models has been shown to progress through a series of stages. Progression of ischemic VF in the in vivo human heart has not been determined. METHODS AND RESULTS: We studied 10 patients undergoing cardiac surgery. Ventricular fibrillation was induced by burst pacing. After 30 seconds, global myocardial ischemia was induced by aortic cross-clamp and maintained for 2.5 minutes, followed by coronary reflow. Epicardial activity was sam...

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Publication status:
Published

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Publisher copy:
10.1161/circep.110.961284

Authors


Bradley, CP More by this author
Clayton, RH More by this author
Hayward, M More by this author
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Journal:
Circulation. Arrhythmia and electrophysiology
Volume:
4
Issue:
5
Pages:
684-691
Publication date:
2011-10-05
DOI:
EISSN:
1941-3084
ISSN:
1941-3149
URN:
uuid:90f96eac-fef0-4a73-91d1-3f9971f4683b
Source identifiers:
170174
Local pid:
pubs:170174

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