Journal article icon

Journal article

Factors influencing the oxygen concentration gradient from the synovial surface of articular cartilage to the cartilage-bone interface: a modeling study.

Abstract:

OBJECTIVE: There is very little information on the gradients of oxygen concentration from the synovial surface to the subchondral bone in articular cartilage. Cartilage is usually regarded as hypoxic, even though cellular metabolism is inhibited at low oxygen concentrations. We therefore measured rates of cellular consumption of oxygen and used these rates to calculate oxygen tension profiles across articular cartilage. METHODS: The rate of oxygen consumption by bovine articular chondrocytes...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/art.20675

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Journal:
Arthritis and rheumatism
Volume:
50
Issue:
12
Pages:
3915-3924
Publication date:
2004-12-05
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
URN:
uuid:90ecebaf-902f-4154-b228-64e6ca536585
Source identifiers:
61905
Local pid:
pubs:61905

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP