- Abstract:
-
5-HT(2C) receptor (5HT(2C)R, serotonin-2C) RNA undergoes editing to produce several receptor variants, some with pharmacological differences. This investigation comprised two parts: the characterisation of 5-HT(2C)R RNA editing in a larger human control sample than previously examined, and a comparative study in subjects with schizophrenia. Secondary structure analysis of the putative edited region of the human 5-HT(2C)R gene predicted the existence of a double stranded (ds) RNA loop, essenti...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/sj.mp.4000920
-
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- Journal:
- Molecular psychiatry
- Volume:
- 6
- Issue:
- 4
- Pages:
- 373-379
- Publication date:
- 2001-07-05
- DOI:
- EISSN:
-
1476-5578
- ISSN:
-
1359-4184
- URN:
-
uuid:90e06d30-1f52-4fb8-80b5-2df15d4d0d5a
- Source identifiers:
-
97933
- Local pid:
- pubs:97933
- Language:
- English
- Keywords:
- Copyright date:
- 2001
Journal article
RNA editing of the 5-HT(2C) receptor is reduced in schizophrenia.
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