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Journal article

RNA editing of the 5-HT(2C) receptor is reduced in schizophrenia.

Abstract:

5-HT(2C) receptor (5HT(2C)R, serotonin-2C) RNA undergoes editing to produce several receptor variants, some with pharmacological differences. This investigation comprised two parts: the characterisation of 5-HT(2C)R RNA editing in a larger human control sample than previously examined, and a comparative study in subjects with schizophrenia. Secondary structure analysis of the putative edited region of the human 5-HT(2C)R gene predicted the existence of a double stranded (ds) RNA loop, essenti...

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Publication status:
Published

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Publisher copy:
10.1038/sj.mp.4000920

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
Journal:
Molecular psychiatry
Volume:
6
Issue:
4
Pages:
373-379
Publication date:
2001-07-05
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
URN:
uuid:90e06d30-1f52-4fb8-80b5-2df15d4d0d5a
Source identifiers:
97933
Local pid:
pubs:97933

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