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Journal article

Impact of cumulative SBP and serious adverse events on efficacy of intensive blood pressure treatment: a randomized clinical trial

Abstract:

BACKGROUND: Intensive blood pressure lowering is increasingly gaining attention. In addition to higher baseline blood pressure, cumulative SBP, visit-to-visit variability, and treatment-induced serious adverse events (SAEs) could impact treatment efficacy over time. Our aim was to assess the impact of cumulative SBP and SAEs on intensive hypertension treatment efficacy in the Systolic Blood Pressure Intervention Trial (SPRINT) population during follow-up.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/HJH.0000000000002001

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Sub department:
Population Health
Oxford college:
St Cross College
Role:
Author
ORCID:
0000-0002-2374-9204
Publisher:
Lippincott, Williams and Wilkins
Journal:
Journal of Hypertension More from this journal
Volume:
37
Issue:
5
Pages:
1058-1069
Publication date:
2019-05-01
Acceptance date:
2018-10-23
DOI:
EISSN:
1473-5598
ISSN:
0263-6352
Pmid:
30444838
Language:
English
Keywords:
Pubs id:
pubs:996184
UUID:
uuid:90b881ad-67e4-464d-be0a-7bfa6e8d8b15
Local pid:
pubs:996184
Source identifiers:
996184
Deposit date:
2019-06-14

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