Interplay of cell-cell signalling and multicellular morphogenesis during Dictyostelium aggregation
- The cellular slime mould Dictyostelium discoideum provides a paradin model system for the study of multicellular pattern formation. Its life cycle involves a route to primitive multicellular organization which has independently evolved in terrestrial species of at least four groups of microorganisms (myxobacteria, acrasiomycota-the cellular slime moulds, myxomycota, and ciliata ). In these species a large number of single cells (nuclei in myxomycota) form through a process of aggregation and differentiation, a fruiting body.
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