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Extracellular cation sensing by the enterocyte: prediction of a novel divalent cation "receptor".

Abstract:

We report that the divalent cation Ni2+ elicits elevations in the cytosolic free Ca2+ concentration ([Ca2+]) in cultured enterocytes. These elevations were monophasic, each response consisting of a rapid initial transient rise of cytosolic [Ca2+] to a peak value followed by an exponential decline. The magnitude of the cytosolic [Ca2+] elevation varied with the concentration of applied Ni2+. In some cells, a single application of Ni2+ induced oscillatory changes in cytosolic [Ca2+]. There was ...

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Publisher copy:
10.1006/bbrc.1995.1748

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Adebanjo, OA More by this author
Shankar, VS More by this author
Colston, KW More by this author
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Journal:
Biochemical and biophysical research communications
Volume:
210
Issue:
3
Pages:
948-953
Publication date:
1995-05-05
DOI:
EISSN:
1090-2104
ISSN:
0006-291X
URN:
uuid:906d63d2-f1c8-4e2e-9f1a-e9a31623285d
Source identifiers:
475696
Local pid:
pubs:475696

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