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Serogroup C meningococcal glycoconjugate vaccine in adolescents: persistence of bactericidal antibodies and kinetics of the immune response to a booster vaccine more than 3 years after immunization.

Abstract:

BACKGROUND: The persistence of protection from meningococcal disease following immunization with serogroup C meningococcal (MenC) glycoconjugate vaccines in infancy is short-lived. The duration of protective immunity afforded by these vaccines in other at-risk age groups (i.e., adolescents and young adults) is not known. We evaluated the persistence of bactericidal antibodies following immunization with a MenC glycoconjugate vaccine (MenCV) in adolescents and the kinetics of immune response t...

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Publication status:
Published

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Publisher copy:
10.1086/508776

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Journal:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume:
43
Issue:
11
Pages:
1387-1394
Publication date:
2006-12-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:905c5a5f-1eda-4eff-b060-0217bda2eac6
Source identifiers:
119431
Local pid:
pubs:119431

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