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Double dissociation of function within the hippocampus: a comparison of dorsal, ventral, and complete hippocampal cytotoxic lesions.

Abstract:

Rats with complete cytotoxic hippocampal lesions exhibited spatial memory impairments in both the water maze and elevated T maze. They were hyperactive in photocell cages; swam faster in the water maze; and were less efficient on a nonspatial, differential reinforcement of low rates (DRL) task. Performance on both spatial tasks was also impaired by selective dorsal but not ventral lesions; swim speed was increased by ventral but not dorsal lesions. Both partial lesions caused a comparable red...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
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Journal:
Behavioral neuroscience
Volume:
113
Issue:
6
Pages:
1170-1188
Publication date:
1999-12-05
DOI:
EISSN:
1939-0084
ISSN:
0735-7044
URN:
uuid:905b1b97-f838-4eda-8249-18d365b245b0
Source identifiers:
10638
Local pid:
pubs:10638

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