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Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells.

Abstract:

The kit ligand (KL), also termed stem cell factor (SCF), is a recently discovered hematopoietic growth factor that augments response of early progenitor cells to other growth factors and supports proliferation of continuous mast cell lines. Histological studies suggest that the receptor for SCF/KL, the c-kit proto-oncogene product, is present in bone marrow megakaryocytes. We studied the effects of SCF/KL on immortalized human megakaryocytic cell lines (CMK, CMK6, and CMK11-5) and on isolated...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Journal:
Blood
Volume:
79
Issue:
2
Pages:
365-371
Publication date:
1992-01-05
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:90598571-1e77-476b-8f36-ebb338d322b0
Source identifiers:
223708
Local pid:
pubs:223708

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