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Antimicrobial resistance prediction and phylogenetic analysis of Neisseria gonorrhoeae isolates using the Oxford Nanopore MinION sequencer

Abstract:

Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is common, compromising gonorrhoea treatment internationally. Rapid characterisation of AMR strains could ensure appropriate and personalised treatment, and support identification and investigation of gonorrhoea outbreaks in nearly real-time. Whole-genome sequencing is ideal for investigation of emergence and dissemination of AMR determinants, predicting AMR, in the gonococcal population and spread of AMR strains in the human...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1038/s41598-018-35750-4

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Big Data Institute
Role:
Author
ORCID:
0000-0002-4162-0228
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Role:
Author
ORCID:
0000-0003-1512-6194
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Publisher:
Nature Research Publisher's website
Journal:
Scientific Reports Journal website
Volume:
8
Issue:
1
Pages:
Article: 17596
Publication date:
2018-12-04
Acceptance date:
2018-11-10
DOI:
EISSN:
2045-2322
Pubs id:
pubs:1020256
URN:
uri:90582c41-6d37-4865-bdb0-1aa35b8f78e7
UUID:
uuid:90582c41-6d37-4865-bdb0-1aa35b8f78e7
Local pid:
pubs:1020256
Language:
English

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