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Haemoglobin E beta thalassaemia in Sri Lanka.

Abstract:

Haemoglobin E beta thalassaemia is the commonest form of severe thalassaemia in many Asian countries, but little is known about its natural history, the reasons for clinical diversity, or its management. We studied 109 Sri Lankan patients with the disorder over 5 years. 25 patients were not receiving transfusion; transfusion was stopped with no deleterious effect in a further 37. We identified several genetic and environmental factors that might contribute to the phenotypic diversity of the d...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Weatherall Insti. of Molecular Medicine
Role:
Author
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Journal:
Lancet (London, England)
Volume:
366
Issue:
9495
Pages:
1467-1470
Publication date:
2005-10-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:90482e27-3857-4813-95bf-dd4153fae184
Source identifiers:
120041
Local pid:
pubs:120041

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