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A reporter assay in lamprey embryos reveals both functional conservation and elaboration of vertebrate enhancers

Abstract:

The sea lamprey is an important model organism for investigating the evolutionary origins of vertebrates. As more vertebrate genome sequences are obtained, evolutionary developmental biologists are becoming increasingly able to identify putative gene regulatory elements across the breadth of the vertebrate taxa. The identification of these regions makes it possible to address how changes at the genomic level have led to changes in developmental gene regulatory networks and ultimately to the e...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Role:
Author
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
9
Issue:
1
Pages:
e85492
Publication date:
2014-01-09
Acceptance date:
2013-12-05
DOI:
EISSN:
1932-6203

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